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shutingsci/README.md

Shu-Ting Yang

Endocrinologist · Pituitary Tumor Center · Medical AI Researcher

神经外科垂体瘤中心内分泌医生 · 医学人工智能研究者

I develop clinically grounded, reproducible research at the intersection of endocrinology, machine learning, and bioinformatics.

Academic profile Google Scholar ORCID Email

About me

I am an endocrinologist at the Pituitary Tumor Center, Department of Neurosurgery, The Sixth Affiliated Hospital of Sun Yat-sen University. My clinical work focuses on pituitary and neuroendocrine disorders, while my research spans diabetes heterogeneity and the translation of computational methods into clinically meaningful patient stratification.

My work connects clinical medicine with:

  • Pituitary and neuroendocrine medicine — multidisciplinary evaluation of pituitary tumors and related endocrine disorders
  • Diabetes phenotyping and classification — identifying meaningful subgroups beyond conventional diagnostic labels
  • Clinical machine learning — developing and evaluating models with attention to discrimination, calibration, transportability, and clinical utility
  • Bioinformatics — investigating disease mechanisms and molecular heterogeneity
  • Clinical epidemiology — cohort studies, survival analysis, risk modelling, and robust sensitivity analyses
  • Responsible medical AI — evaluating AI systems under real-world clinical constraints

Selected research

  • Real-world performance of open-source large language models in diabetes diagnosis
    Frontiers in Endocrinology, 2026 · Article

  • A new vision of diabetes classification: A shift from clinical manifestation to etiological molecular mechanism
    Journal of Practical Medicine, 2024 · DOI

  • Application of the Chinese Expert Consensus on Diabetes Classification in Clinical Practice
    Chinese Journal of Internal Medicine, 2023 · PubMed

  • Validation of the Swedish diabetes re-grouping scheme in adult-onset diabetes in China
    The Journal of Clinical Endocrinology & Metabolism, 2020 · PubMed

Current interests

  • Multidisciplinary research on pituitary tumors, endocrine phenotypes, and clinically relevant outcomes
  • Reproducible workflows spanning study design, analysis, peer review, and publication
  • Public-cohort and real-world-data research with explicit evidence and validation boundaries
  • Medical AI evaluation that prioritizes clinical relevance over model complexity
  • Research infrastructure for a focused, AI-assisted one-person lab

Working principles

Clinical relevance before model complexity.
Reproducibility before novelty claims.
Transparent negative results and clear evidence boundaries.

Open-source workflow

I maintain personal forks of the One Person Lab workflow stack while adapting it to medical-research practice:

  • one-person-lab — a federated gateway for a focused research lab
  • opl-flow — reusable Codex workflows for research and project execution

Connect

Popular repositories Loading

  1. opl-flow opl-flow Public

    Forked from gaofeng21cn/opl-flow

    OPL Flow Codex workflow plugin and reusable local profile

    Python

  2. one-person-lab one-person-lab Public

    Forked from gaofeng21cn/one-person-lab

    Top-level gateway federation for a one-person research lab across domain systems and shared foundations.

    TypeScript

  3. shutingsci shutingsci Public

    Pituitary and neuroendocrine medicine · Clinical research · Medical AI